Involvement of PrP(C) in kainate-induced excitotoxicity in several mouse strains

The cellular prion protein (PrP(C)) has been associated with a plethora of cellular functions ranging from cell cycle to neuroprotection. Mice lacking PrP(C) show an increased susceptibility to epileptic seizures; the protein, then, is neuroprotective. However, lack of experimental reproducibility h...

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Pubblicato in:Sci Rep
Autori principali: Carulla, Patricia, Llorens, Franc, Matamoros-Angles, Andreu, Aguilar-Calvo, Patricia, Espinosa, Juan Carlos, Gavín, Rosalina, Ferrer, Isidre, Legname, Giuseppe, Torres, Juan Maria, del Río, José A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648388/
https://ncbi.nlm.nih.gov/pubmed/26155834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11971
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