Roux-en-Y Gastric Bypass Acutely Decreases Protein Carbonylation and Increases Expression of Mitochondrial Biogenesis Genes in Subcutaneous Adipose Tissue

BACKGROUND: Mitochondrial dysfunction in adipose tissue has been implicated as a pathogenic step in the development of type 2 diabetes mellitus (T2DM). In adipose tissue, chronic nutrient overload results in mitochondria driven increased reactive oxygen species (ROS) leading to carbonylation of prot...

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Veröffentlicht in:Obes Surg
Hauptverfasser: Jahansouz, Cyrus, Serrot, Federico J., Frohnert, Brigitte I., Foncea, Rocio E., Dorman, Robert B., Slusarek, Bridget, Leslie, Daniel B., Bernlohr, David A., Ikramuddin, Sayeed
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648364/
https://ncbi.nlm.nih.gov/pubmed/25975200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11695-015-1708-5
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