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pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI

BACKGROUND: Interstitial tissue acidosis resulting from abnormal perfusion and metabolism is a hallmark of cancer. The current study demonstrates that chemical exchange saturation transfer (CEST) MRI can be used as a noninvasive pH-weighted molecular imaging technique by targeting the chemical excha...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Harris, Robert J., Cloughesy, Timothy F., Liau, Linda M., Prins, Robert M., Antonios, Joseph P., Li, Debiao, Yong, William H., Pope, Whitney B., Lai, Albert, Nghiemphu, Phioanh L., Ellingson, Benjamin M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648305/
https://ncbi.nlm.nih.gov/pubmed/26113557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov106
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