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Molecular Basis of Electrophilic and Oxidative Defense: Promises and Perils of Nrf2

Induction of drug-metabolizing enzymes through the antioxidant response element (ARE)-dependent transcription was initially implicated in chemoprevention against cancer by antioxidants. Recent progress in understanding the biology and mechanism of induction revealed a critical role of induction in c...

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Detalhes bibliográficos
Publicado no:Pharmacol Rev
Main Authors: Ma, Qiang, He, Xiaoqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648289/
https://ncbi.nlm.nih.gov/pubmed/22966037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.110.004333
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