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Abnormal Newborn Screening Data and Acylcarnitines in HIV/ARV-Exposed Infants

BACKGROUND: Antiretroviral drugs (ARV), specifically nucleoside analogs, are toxic to mitochondrial oxidative phosphorylation (OXPHOS). Other metabolic pathways, such as fatty acid oxidation, organic acid metabolism and amino acid metabolism, are dependent on normal OXPHOS but remain unexamined as p...

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Detalhes bibliográficos
Publicado no:Pediatr Infect Dis J
Main Authors: Kirmse, Brian, Hobbs, Charlotte V., Peter, Inga, LaPlante, Bryan, Caggana, Michele, Kloke, Karen, Raymond, Kimiyo, Summar, Marshall, Borkowsky, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648253/
https://ncbi.nlm.nih.gov/pubmed/22935866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0b013e31827030a6
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