Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia

The heritability of B cell chronic lymphocytic leukemia (CLL) is relatively high; however, no predisposing mutation has been convincingly identified. We show that loss or reduced expression of death-associated protein kinase 1 (DAPK1) underlies cases of heritable predisposition to CLL and the majori...

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Publicado no:Cell
Main Authors: Raval, Aparna, Tanner, Stephan M., Byrd, John C., Angerman, Elizabeth B., Perko, James D., Chen, Shih-Shih, Hackanson, Björn, Grever, Michael R., Lucas, David M., Matkovic, Jennifer J., Lin, Thomas S., Kipps, Thomas J., Murray, Fiona, Weisenburger, Dennis, Sanger, Warren, Lynch, Jane, Watson, Patrice, Jansen, Mary, Yoshinaga, Yuko, Rosenquist, Richard, de Jong, Pieter J., Coggill, Penny, Beck, Stephan, Lynch, Henry, de la Chapelle, Albert, Plass, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647864/
https://ncbi.nlm.nih.gov/pubmed/17540169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.03.043
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