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Integrated genomics approach to identify biologically relevant alterations in fewer samples
BACKGROUND: Several statistical tools have been developed to identify genes mutated at rates significantly higher than background, indicative of positive selection, involving large sample cohort studies. However, studies involving smaller sample sizes are inherently restrictive due to their limited...
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Publicado no: | BMC Genomics |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647579/ https://ncbi.nlm.nih.gov/pubmed/26572163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2138-4 |
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