High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effect

BACKGROUND: Epidemiological studies have indicated significant associations of leukocyte mitochondrial DNA (mtDNA) copy number with risk of several malignancies, including glioma. However, whether mtDNA content can predict the clinical outcome of glioma patients has not been investigated. METHODS: T...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Chen, Y, Zhang, J, Huang, X, Zhou, X, Hu, J, Li, G, He, S, Xing, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647544/
https://ncbi.nlm.nih.gov/pubmed/26022928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.184
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