High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effect

BACKGROUND: Epidemiological studies have indicated significant associations of leukocyte mitochondrial DNA (mtDNA) copy number with risk of several malignancies, including glioma. However, whether mtDNA content can predict the clinical outcome of glioma patients has not been investigated. METHODS: T...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Chen, Y, Zhang, J, Huang, X, Zhou, X, Hu, J, Li, G, He, S, Xing, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647544/
https://ncbi.nlm.nih.gov/pubmed/26022928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.184
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