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Stem vs non-stem cell origin of colorectal cancer

Colorectal cancer (CRC) is one of the most common cancers in the western world and is characterised by deregulation of the Wnt signalling pathway. Mutation of the adenomatous polyposis coli (APC) tumour suppressor gene, which encodes a protein that negatively regulates this pathway, occurs in almost...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Huels, D J, Sansom, O J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647531/
https://ncbi.nlm.nih.gov/pubmed/26110974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.214
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