Sequence-specific scission of DNA by the chemical nuclease activity of 1,10-phenanthroline-copper(I) targeted by RNA.

RNAs modified with the chemical nuclease 1,10-phenanthroline-copper(I) can achieve the sequence-specific scission of single- and double-stranded DNA targets. The RNAs are prepared in vitro by using 5-(3-aminoallyl)-UTP as the sole source of UTP and can be readily modified with 1,10-phenanthroline by...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Chen, C B, Gorin, M B, Sigman, D S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7683427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4206
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