MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivo

BACKGROUND: XBP1 is a key transcription factor of the unfolded protein response in mammalian cells, which is involved in several cardiovascular pathological progression including cardiac hypertrophy and myocardial infarction, but its expression trend, function and upstream regulate mechanism in the...

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Udgivet i:J Transl Med
Main Authors: Duan, Quanlu, Chen, Chen, Yang, Lei, Li, Ni, Gong, Wei, Li, Sheng, Wang, Dao Wen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647486/
https://ncbi.nlm.nih.gov/pubmed/26572862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0725-4
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