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Integrity of the core mitochondrial RNA-binding complex 1 is vital for trypanosome RNA editing

Trypanosoma brucei is the causative agent of the human and veterinarian diseases African sleeping sickness and nagana. A majority of its mitochondrial-encoded transcripts undergo RNA editing, an essential process of post-transcriptional uridine insertion and deletion to produce translatable mRNA. Be...

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Dettagli Bibliografici
Pubblicato in:RNA
Autori principali: Huang, Zhenqiu, Faktorová, Drahomíra, Křížová, Adéla, Kafková, Lucie, Read, Laurie K., Lukeš, Julius, Hashimi, Hassan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647463/
https://ncbi.nlm.nih.gov/pubmed/26447184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052340.115
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