Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis

BACKGROUND: FKBP51 is overexpressed in melanoma and impacts tumour cell properties. However, its comprehensive role in melanoma pathogenesis and underlying mechanism(s) remain elusive. METHODS: FKBP51 was stably silenced in aggressive melanoma cell lines and its effect examined in vitro and in mouse...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Srivastava, S K, Bhardwaj, A, Arora, S, Tyagi, N, Singh, A P, Carter, J E, Scammell, J G, Fodstad, Ø, Singh, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647250/
https://ncbi.nlm.nih.gov/pubmed/25942396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.154
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