Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine

Copper-catalyzed aerobic oxidative C–H/N–H coupling between simple ketones and diamines was developed toward the synthesis of a variety of pyrazines. Various substituted ketones were compatible for this transformation. Preliminary mechanistic investigations indicated that radical species were involv...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Wu, Kun, Huang, Zhiliang, Qi, Xiaotian, Li, Yingzi, Zhang, Guanghui, Liu, Chao, Yi, Hong, Meng, Lingkui, Bunel, Emilio E., Miller, Jeffrey T., Pao, Chih-Wen, Lee, Jyh-Fu, Lan, Yu, Lei, Aiwen
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2015
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646816/
https://ncbi.nlm.nih.gov/pubmed/26601302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500656
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