Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo

Adaptive immunity is mediated by antigen receptors that can induce weak or strong immune responses depending on the nature of the antigen that is bound. In T lymphocytes, antigen recognition triggers signal transduction by clustering T cell receptor (TCR)/CD3 multiprotein complexes. In addition, it...

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Vydáno v:Sci Adv
Hlavní autoři: Hoffmann, Michele M., Molina-Mendiola, Carlos, Nelson, Alfreda D., Parks, Christopher A., Reyes, Edwin E., Hansen, Michael J., Rajagopalan, Govindarajan, Pease, Larry R., Schrum, Adam G., Gil, Diana
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646799/
https://ncbi.nlm.nih.gov/pubmed/26601285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500415
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