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Inferring the Clonal Structure of Viral Populations from Time Series Sequencing

RNA virus populations will undergo processes of mutation and selection resulting in a mixed population of viral particles. High throughput sequencing of a viral population subsequently contains a mixed signal of the underlying clones. We would like to identify the underlying evolutionary structures....

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Pubblicato in:PLoS Comput Biol
Autori principali: Chedom, Donatien F., Murcia, Pablo R., Greenman, Chris D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646700/
https://ncbi.nlm.nih.gov/pubmed/26571026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004344
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