Changes in Carboxy Methylation and Tyrosine Phosphorylation of Protein Phosphatase PP2A Are Associated with Epididymal Sperm Maturation and Motility

Mammalian sperm contain the serine/threonine phosphatases PP1γ2 and PP2A. The role of sperm PP1γ2 is relatively well studied. Here we confirm the presence of PP2A in sperm and show that it undergoes marked changes in methylation (leucine 309), tyrosine phosphorylation (tyrosine 307) and catalytic ac...

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Pubblicato in:PLoS One
Autori principali: Dudiki, Tejasvi, Kadunganattil, Suraj, Ferrara, John K., Kline, Douglas W., Vijayaraghavan, Srinivasan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646675/
https://ncbi.nlm.nih.gov/pubmed/26569399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141961
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