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A Long-Term High-Fat/High-Sucrose Diet Promotes Kidney Lipid Deposition and Causes Apoptosis and Glomerular Hypertrophy in Bama Minipigs

Metabolic syndrome can induce chronic renal injury in humans. In the present study, Bama minipigs were fed a high-fat/high-sucrose diet (HFHSD) for 23 months, which caused them to develop the pathological characteristics of metabolic syndrome, including obesity, hyperinsulinemia, and hyperlipidemia,...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Li, Li, Zhao, Zhanzhao, Xia, Jihan, Xin, Leilei, Chen, Yaoxing, Yang, Shulin, Li, Kui
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646641/
https://ncbi.nlm.nih.gov/pubmed/26571016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142884
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