A Long-Term High-Fat/High-Sucrose Diet Promotes Kidney Lipid Deposition and Causes Apoptosis and Glomerular Hypertrophy in Bama Minipigs

Metabolic syndrome can induce chronic renal injury in humans. In the present study, Bama minipigs were fed a high-fat/high-sucrose diet (HFHSD) for 23 months, which caused them to develop the pathological characteristics of metabolic syndrome, including obesity, hyperinsulinemia, and hyperlipidemia,...

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Veröffentlicht in:PLoS One
Hauptverfasser: Li, Li, Zhao, Zhanzhao, Xia, Jihan, Xin, Leilei, Chen, Yaoxing, Yang, Shulin, Li, Kui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646641/
https://ncbi.nlm.nih.gov/pubmed/26571016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142884
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