A Long-Term High-Fat/High-Sucrose Diet Promotes Kidney Lipid Deposition and Causes Apoptosis and Glomerular Hypertrophy in Bama Minipigs

Metabolic syndrome can induce chronic renal injury in humans. In the present study, Bama minipigs were fed a high-fat/high-sucrose diet (HFHSD) for 23 months, which caused them to develop the pathological characteristics of metabolic syndrome, including obesity, hyperinsulinemia, and hyperlipidemia,...

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Bibliographic Details
Published in:PLoS One
Main Authors: Li, Li, Zhao, Zhanzhao, Xia, Jihan, Xin, Leilei, Chen, Yaoxing, Yang, Shulin, Li, Kui
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646641/
https://ncbi.nlm.nih.gov/pubmed/26571016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142884
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