NGF Modulates trkA(NGFR)/p75(NTR) in αSMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP)

OBJECTIVE: In a previous study, we reported the upregulation of Nerve Growth Factor (NGF) and trkA(NGFR) expression in Ocular Cicatricial Pemphigoid (OCP), an inflammatory and remodeling eye disease. Herein, we hypothesize a potential NGF-driven mechanism on fibroblasts (FBs) during OCP remodeling e...

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Udgivet i:PLoS One
Main Authors: Micera, Alessandra, Stampachiacchiere, Barbara, Di Zazzo, Antonio, Sgrulletta, Roberto, Cortes, Magdalena, Normando, Eduardo Maria, Lambiase, Alessandro, Bonini, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646573/
https://ncbi.nlm.nih.gov/pubmed/26569118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142737
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