The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway

Interleukin-33 (IL-33) plays a protective role in myocardial ischemia and reperfusion (I/R) injury, but the underlying mechanism was not fully elucidated. The present study was designed to investigate whether IL-33 protects against myocardial I/R injury by regulating both P38 mitogen-activated-prote...

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Vydáno v:PLoS One
Hlavní autoři: Ruisong, Ma, Xiaorong, Hu, Gangying, Hu, Chunfeng, Yi, Changjiang, Zhang, Xuefei, Li, Yuanhong, Li, Hong, Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646496/
https://ncbi.nlm.nih.gov/pubmed/26571038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143064
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