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Genome-Wide Locations of Potential Epimutations Associated with Environmentally Induced Epigenetic Transgenerational Inheritance of Disease Using a Sequential Machine Learning Prediction Approach

Environmentally induced epigenetic transgenerational inheritance of disease and phenotypic variation involves germline transmitted epimutations. The primary epimutations identified involve altered differential DNA methylation regions (DMRs). Different environmental toxicants have been shown to promo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Haque, M. Muksitul, Holder, Lawrence B., Skinner, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646459/
https://ncbi.nlm.nih.gov/pubmed/26571271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142274
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