Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases

Acyl-CoA mutases are a growing class of adenosylcobalamin-dependent radical enzymes that perform challenging carbon skeleton rearrangements in primary and secondary metabolism. Members of this class of enzymes must precisely control substrate positioning to prevent oxidative interception of radical...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Jost, Marco, Born, David A., Cracan, Valentin, Banerjee, Ruma, Drennan, Catherine L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646380/
https://ncbi.nlm.nih.gov/pubmed/26318610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676890
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