Mouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner

Siglec-1 (sialoadhesin, CD169) is a surface receptor on human cells that mediates trans-enhancement of HIV-1 infection through recognition of sialic acid moieties in virus membrane gangliosides. Here, we demonstrate that mouse Siglec-1, expressed on the surface of primary macrophages in an interfero...

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Pubblicato in:J Biol Chem
Autori principali: Erikson, Elina, Wratil, Paul R., Frank, Martin, Ambiel, Ina, Pahnke, Katharina, Pino, Maria, Azadi, Parastoo, Izquierdo-Useros, Nuria, Martinez-Picado, Javier, Meier, Chris, Schnaar, Ronald L., Crocker, Paul R., Reutter, Werner, Keppler, Oliver T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646371/
https://ncbi.nlm.nih.gov/pubmed/26370074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681338
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