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Tubulin Tail Sequences and Post-translational Modifications Regulate Closure of Mitochondrial Voltage-dependent Anion Channel (VDAC)

It was previously shown that tubulin dimer interaction with the mitochondrial outer membrane protein voltage-dependent anion channel (VDAC) blocks traffic through the channel and reduces oxidative metabolism and that this requires the unstructured anionic C-terminal tail peptides found on both α- an...

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Pubblicato in:J Biol Chem
Autori principali: Sheldon, Kely L., Gurnev, Philip A., Bezrukov, Sergey M., Sackett, Dan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646331/
https://ncbi.nlm.nih.gov/pubmed/26306046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678854
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