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The Synergistic Enhancement of Cloning Efficiency in Individualized Human Pluripotent Stem Cells by Peroxisome Proliferative-activated Receptor-γ (PPARγ) Activation and Rho-associated Kinase (ROCK) Inhibition

Although human pluripotent stem cells (hPSCs) provide valuable sources for regenerative medicine, their applicability is dependent on obtaining both suitable up-scaled and cost effective cultures. The Rho-associated kinase (ROCK) inhibitor Y-27632 permits hPSC survival upon dissociation; however, cl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kajabadi, Nasim-Sadat, Ghoochani, Ali, Peymani, Maryam, Ghaedi, Kamran, Kiani-Esfahani, Abbas, Hashemi, Motahareh-Sadat, Nasr-Esfahani, Mohammad Hossein, Baharvand, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646278/
https://ncbi.nlm.nih.gov/pubmed/26336103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.624841
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