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Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein

Human T-cell leukemia virus (HTLV) type 1, the etiological agent of adult T-cell leukemia, expresses the viral oncoprotein Tax1. In contrast, HTLV-2, which expresses Tax2, is non-leukemogenic. One difference between these homologous proteins is the presence of a C-terminal PDZ domain-binding motif (...

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Vydáno v:J Biol Chem
Hlavní autoři: Cherian, Mathew A., Baydoun, Hicham H., Al-Saleem, Jacob, Shkriabai, Nikoloz, Kvaratskhelia, Mamuka, Green, Patrick, Ratner, Lee
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646275/
https://ncbi.nlm.nih.gov/pubmed/26324707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684746
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