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Kin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That Regulates Basal Insulin Secretion

Direct interactions among pancreatic β-cells via cell surface proteins inhibit basal and enhance stimulated insulin secretion. Here, we functionally and biochemically characterized Kirrel2, an immunoglobulin superfamily protein with β-cell-specific expression in the pancreas. Our results show that K...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Yesildag, Burcak, Bock, Thomas, Herrmanns, Karolin, Wollscheid, Bernd, Stoffel, Markus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646245/
https://ncbi.nlm.nih.gov/pubmed/26324709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684704
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