The Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) represents an anomalous subset of breast cancer with a greatly reduced (30%) 5-year survival rate. The enhanced mortality and morbidity of TNBC arises from the high metastatic rate, which requires the acquisition of AnR, a process whereby anchorage-dependent cell...

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Foilsithe in:J Biol Chem
Main Authors: Johnson, Ryan M., Vu, Ngoc T., Griffin, Brian P., Gentry, Amanda E., Archer, Kellie J., Chalfant, Charles E., Park, Margaret A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2015
Ábhair:
Gene Regulation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646214/
https://ncbi.nlm.nih.gov/pubmed/26304115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.671206
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