Bacteriophage-mediated Glucosylation Can Modify Lipopolysaccharide O-Antigens Synthesized by an ATP-binding Cassette (ABC) Transporter-dependent Assembly Mechanism

Lysogenic bacteriophages may encode enzymes that modify the structures of lipopolysaccharide O-antigen glycans, altering the structure of the bacteriophage receptor and resulting in serotype conversion. This can enhance virulence and has implications for antigenic diversity and vaccine development....

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Mann, Evan, Ovchinnikova, Olga G., King, Jerry D., Whitfield, Chris
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646201/
https://ncbi.nlm.nih.gov/pubmed/26330553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.660803
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