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Structure of the Bacillus anthracis Sortase A Enzyme Bound to Its Sorting Signal: A FLEXIBLE AMINO-TERMINAL APPENDAGE MODULATES SUBSTRATE ACCESS

The endospore forming bacterium Bacillus anthracis causes lethal anthrax disease in humans and animals. The ability of this pathogen to replicate within macrophages is dependent upon the display of bacterial surface proteins attached to the cell wall by the B. anthracis Sortase A ((Ba)SrtA) enzyme....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chan, Albert H., Yi, Sung Wook, Terwilliger, Austen L., Maresso, Anthony W., Jung, Michael E., Clubb, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646193/
https://ncbi.nlm.nih.gov/pubmed/26324714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.670984
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