Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor

Two recently discovered groups of prokaryotic di-metal carboxylate proteins harbor a heterodinuclear Mn/Fe cofactor. These are the class Ic ribonucleotide reductase R2 proteins and a group of oxidases that are found predominantly in pathogens and extremophiles, called R2-like ligand-binding oxidases...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Griese, Julia J., Kositzki, Ramona, Schrapers, Peer, Branca, Rui M. M., Nordström, Anders, Lehtiö, Janne, Haumann, Michael, Högbom, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646176/
https://ncbi.nlm.nih.gov/pubmed/26324712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675223
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