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Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells
Glioblastomas display hierarchies with self-renewing cancer stem-like cells (CSCs). RNA sequencing and enhancer mapping revealed regulatory programs unique to CSCs causing upregulation of the iron transporter transferrin, the top differentially expressed gene compared to tissue-specific progenitors....
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| Publicado en: | Cancer Cell |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646058/ https://ncbi.nlm.nih.gov/pubmed/26461092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.09.002 |
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