Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly

The risk of liver cancer in patients infected with the hepatitis B virus (HBV) and their clinical response to interferon alpha therapy vary based on the HBV genotype. The mechanisms underlying these differences in HBV pathogenesis remain unclear. In HepG2 cells transfected with a mutant HBV(G2335A)...

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Publicado en:J Virol
Autores principales: Tsai, Kuen-Nan, Chong, Chin-Liew, Chou, Yu-Chi, Huang, Chien-Chiao, Wang, Yi-Ling, Wang, Shao-Win, Chen, Mong-Liang, Chen, Chun-Hong, Chang, Chungming
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645676/
https://ncbi.nlm.nih.gov/pubmed/26339052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00949-15
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