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HuR Displaces Polypyrimidine Tract Binding Protein To Facilitate La Binding to the 3′ Untranslated Region and Enhances Hepatitis C Virus Replication

HuR is a ubiquitous, RNA binding protein that influences the stability and translation of several cellular mRNAs. Here, we report a novel role for HuR, as a regulator of proteins assembling at the 3′ untranslated region (UTR) of viral RNA in the context of hepatitis C virus (HCV) infection. HuR relo...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Shwetha, Shivaprasad, Kumar, Anuj, Mullick, Ranajoy, Vasudevan, Deeptha, Mukherjee, Nilanjan, Das, Saumitra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645635/
https://ncbi.nlm.nih.gov/pubmed/26339049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01714-15
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