Signal Transduction by BvgS Sensor Kinase: BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY

The two-component sensory transduction system BvgAS controls the virulence regulon of the whooping-cough agent Bordetella pertussis. The periplasmic moiety of the homodimeric sensor kinase BvgS is composed of four bilobed Venus flytrap (VFT) perception domains followed by α helices that extend into...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dupré, Elian, Lesne, Elodie, Guérin, Jérémy, Lensink, Marc F., Verger, Alexis, de Ruyck, Jérôme, Brysbaert, Guillaume, Vezin, Hervé, Locht, Camille, Antoine, Rudy, Jacob-Dubuisson, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645585/
https://ncbi.nlm.nih.gov/pubmed/26203186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.655720
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