Infectious Bronchitis Coronavirus Inhibits STAT1 Signaling and Requires Accessory Proteins for Resistance to Type I Interferon Activity

The innate immune response is the first line of defense against viruses, and type I interferon (IFN) is a critical component of this response. Similar to other viruses, the gammacoronavirus infectious bronchitis virus (IBV) has evolved under evolutionary pressure to evade and counteract the IFN resp...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kint, Joeri, Dickhout, Annemiek, Kutter, Jasmin, Maier, Helena J., Britton, Paul, Koumans, Joseph, Pijlman, Gorben P., Fros, Jelke J., Wiegertjes, Geert F., Forlenza, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645315/
https://ncbi.nlm.nih.gov/pubmed/26401035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01057-15
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