Genomic Analysis, Phenotype, and Virulence of the Historical Brazilian Smallpox Vaccine Strain IOC: Implications for the Origins and Evolutionary Relationships of Vaccinia Virus

Smallpox was declared eradicated in 1980 after an intensive vaccination program using different strains of vaccinia virus (VACV; Poxviridae). VACV strain IOC (VACV-IOC) was the seed strain of the smallpox vaccine manufactured by the major vaccine producer in Brazil during the smallpox eradication pr...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Medaglia, Maria Luiza G., Moussatché, Nissin, Nitsche, Andreas, Dabrowski, Pjotr Wojtek, Li, Yu, Damon, Inger K., Lucas, Carolina G. O., Arruda, Luciana B., Damaso, Clarissa R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645304/
https://ncbi.nlm.nih.gov/pubmed/26378174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01833-15
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