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Human Cytomegalovirus pUL93 Is Required for Viral Genome Cleavage and Packaging

Human cytomegalovirus (HCMV) pUL93 is essential for virus growth, but its precise function in the virus life cycle is unknown. Here, we characterize a UL93 stop mutant virus (UL93st-TB40/E-BAC) to demonstrate that the absence of this protein does not restrict viral gene expression; however, cleavage...

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Vydáno v:J Virol
Hlavní autoři: DeRussy, Bernadette M., Tandon, Ritesh
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645300/
https://ncbi.nlm.nih.gov/pubmed/26401033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02382-15
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