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Human Cytomegalovirus pUL93 Is Required for Viral Genome Cleavage and Packaging

Human cytomegalovirus (HCMV) pUL93 is essential for virus growth, but its precise function in the virus life cycle is unknown. Here, we characterize a UL93 stop mutant virus (UL93st-TB40/E-BAC) to demonstrate that the absence of this protein does not restrict viral gene expression; however, cleavage...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: DeRussy, Bernadette M., Tandon, Ritesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645300/
https://ncbi.nlm.nih.gov/pubmed/26401033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02382-15
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