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Transcriptional activation of low density lipoprotein receptor gene by angiotensin-converting enzyme inhibitors and Ca(2+)-channel blockers involves protein kinase C isoforms.

The pharmacological potency of angiotensin-converting enzyme (ACE) inhibitors (lisinopril and enalaprilat) on the transcription of low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase genes was examined in human vascular smooth muscle cells and compared with the action of Ca...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Block, L H, Keul, R, Crabos, M, Ziesche, R, Roth, M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46453/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7683421/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4097
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