Silicon Incorporated Morpholine Antifungals: Design, Synthesis, and Biological Evaluation

[Image: see text] Known morpholine class antifungals (fenpropimorph, fenpropidin, and amorolfine) were synthetically modified through silicon incorporation to have 15 sila-analogues. Twelve sila-analogues exhibited potent antifungal activity against different human fungal pathogens such as Candida a...

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Publicat a:ACS Med Chem Lett
Autors principals: Jachak, Gorakhnath R., Ramesh, Remya, Sant, Duhita G., Jorwekar, Shweta U., Jadhav, Manjusha R., Tupe, Santosh G., Deshpande, Mukund V., Reddy, D. Srinivasa
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645241/
https://ncbi.nlm.nih.gov/pubmed/26617963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00245
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