A carregar...
Design and Synthesis of a Focused Library of Diamino Triazines as Potential Mycobacterium tuberculosis DHFR Inhibitors
[Image: see text] We report design of a series of 2,4-diamino triazines as Mycobacterium tuberculosis (Mtb) dihydrofolate reductase inhibitors. The synthesized compounds were evaluated against Mtb (H(37)Rv and Dormant stage H(37)Ra), their cytotoxicity was assessed (HepG2 and A549 cell lines), and s...
Na minha lista:
| Publicado no: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2015
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645240/ https://ncbi.nlm.nih.gov/pubmed/26617968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00367 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|