Evasion of protective immunity by Borrelia burgdorferi by truncation of outer surface protein B.

We analyzed variability in outer surface protein B (OspB) from Borrelia burgdorferi (Bb), the causative agent of Lyme disease, to determine how Bb escapes immune destruction. We have shown that vaccination with OspB from Bb strain B31 protected mice from infection with Bb B31 but not against Bb N40....

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fikrig, E, Tao, H, Kantor, F S, Barthold, S W, Flavell, R A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46452/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7683420/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4092
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