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A controlled antibiotic release system to prevent orthopedic-implant associated infections: An in vitro study

A new device for local delivery of antibiotics is presented, with potential use as a drug-eluting fixation pin for orthopedic applications. The implant consists of a stainless steel hollow tubular reservoir packed with the desired antibiotic. Release takes place through several orifices previously d...

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Détails bibliographiques
Publié dans:Eur J Pharm Biopharm
Auteurs principaux: Gimeno, Marina, Pinczowski, Pedro, Pérez, Marta, Giorello, Antonella, Martínez, Miguel Ángel, Santamaría, Jesús, Arruebo, Manuel, Luján, Lluís
Format: Artigo
Langue:Inglês
Publié: Elsevier Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644989/
https://ncbi.nlm.nih.gov/pubmed/26297104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2015.08.007
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