MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization

Observational cohort studies can provide rich datasets with a diverse range of phenotypic variables. However, hypothesis-driven epidemiological analyses by definition only test particular hypotheses chosen by researchers. Furthermore, observational analyses may not provide robust evidence of causali...

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Udgivet i:Sci Rep
Main Authors: Millard, Louise A. C., Davies, Neil M., Timpson, Nic J., Tilling, Kate, Flach, Peter A., Smith, George Davey
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644974/
https://ncbi.nlm.nih.gov/pubmed/26568383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16645
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