Brazilin isolated from the heartwood of Caesalpinia sappan L induces endothelium-dependent and -independent relaxation of rat aortic rings

AIM: Brazilin is one of the major constituents of Caesalpinia sappan L with various biological activities. This study sought to investigate the vasorelaxant effect of brazilin on isolated rat thoracic aorta and explore the underlying mechanisms. METHODS: Endothelium-intact and -denuded aortic rings...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Yan, Yu, Chen, Yu-cai, Lin, Yi-huang, Guo, Jing, Niu, Zi-ran, Li, Li, Wang, Shou-bao, Fang, Lian-hua, Du, Guan-hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644902/
https://ncbi.nlm.nih.gov/pubmed/26564314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.113
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