The Role and Mechanism of α-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells

Objective. To investigate the role and possible mechanism of α-Klotho in the calcification and the osteogenic transition of cultured VSMCs. Methods. VSMCs were cultured in vitro and divided into 5 groups, each using a different medium: (1) control; (2) β-GP; (3) β-GP + Klotho; (4) β-GP + LiCl; (5) β...

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Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Chen, Tianlei, Mao, Huijuan, Chen, Cheng, Wu, Lin, Wang, Ningning, Zhao, Xiufen, Qian, Jun, Xing, Changying
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644825/
https://ncbi.nlm.nih.gov/pubmed/26609522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/194362
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