Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377

BACKGROUND: Micro ribonucleic acid (miR) dysregulation in the myocardium has been implicated in cardiac remodeling after injury or stress. OBJECTIVES: This study sought to explore the role of miR in human CD34(+) cell (hCD34(+)) dysfunction in vivo after transplantation into the myocardium under isc...

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Veröffentlicht in:J Am Coll Cardiol
Hauptverfasser: Joladarashi, Darukeshwara, Garikipati, Venkata Naga Srikanth, Thandavarayan, Rajarajan A., Verma, Suresh K., Mackie, Alexander R., Khan, Mohsin, Gumpert, Anna M., Bhimaraj, Arvind, Youker, Keith A., Uribe, Cesar, Babu, Sahana Suresh, Jeyabal, Prince, Kishore, Raj, Krishnamurthy, Prasanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644493/
https://ncbi.nlm.nih.gov/pubmed/26564600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2015.09.009
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