Transient receptor potential ankyrin 1 that is induced in dorsal root ganglion neurons contributes to acute cold hypersensitivity after oxaliplatin administration

BACKGROUND: Peripheral cold neuropathic pain is a serious side effect of oxaliplatin treatment. However, the mechanism of oxaliplatin-induced cold hyperalgesia is unknown. In the present study, we investigated the effects of oxaliplatin on transient receptor potential ankyrin 1 (TRPA1) in dorsal roo...

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Pubblicato in:Mol Pain
Autori principali: Yamamoto, Ken, Chiba, Noriko, Chiba, Terumasa, Kambe, Toshie, Abe, Kenji, Kawakami, Kazuyoshi, Utsunomiya, Iku, Taguchi, Kyoji
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644342/
https://ncbi.nlm.nih.gov/pubmed/26567040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12990-015-0072-8
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